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Grant Forms Novel Research Partnership Between Sanford-Burnham and U.S. Air Force


A new project underway at the Sanford-Burnham Medical Research Institute is expected to reduce the need for laboratory animals. Scientists are now able to use stem cells instead.

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[The Sanford-Burnham Medical Research Institute in Orlando]

A three year grant from the U-S Air Force will allow Sanford Burnham to assess the potential toxicity of large collections of chemicals.  It’s work that would normally rely on animal testing. But this research will instead use pluripotent stem cells that are genetically reprogrammed adult cells. Siobhan Malany is a chemical biology team leader at Sanford Burnham’s Conrad Prebys Center for Chemical Genomics.  She says using lab animals to test toxicity requires long term studies.  Stem cells will net faster results.

“It certainly will lower the use of animal studies, and that’s the whole point, to be more cost effective by using a cell based model that’s relevant to human biology and also just to decrease the reliance on animal studies,” she says.

Researchers from both the Orlando and California Sanford-Burnham campuses are participating in the research.